Publication 2014-2016
Role of Plasmodium vivax Duffy-binding protein 1 in invasion of Duffy-null Africans
Background: The ability of the malaria parasite Plasmodium vivax to invade erythrocytes is dependent on the expression of the Duffy blood group antigen on erythrocytes. Consequently, Africans who are null for the Duffy antigen are not susceptible to P. vivax infections...........
Read More2016
Independent Origin and Global Distribution of Distinct Plasmodium vivax Duffy Binding Protein Gene Duplications
Background: Plasmodium vivax causes the majority of malaria episodes outside Africa, but remains a relatively understudied pathogen. The pathology of P. vivax infection depends critically on the parasite’s ability to..........
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Seasonal dynamics, longevity, and biting activity of anopheline mosquitoes in southwestern Ethiopia
Background: Continuous monitoring of vector species composition, abundance, dynamics, feeding pattern, and host finding strategy is the base to determine when, what, and how control should ........
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Malaria related perceptions, care seeking after onset of fever and anti-malarial drug use in malaria endemic settings of southwest Ethiopia
Background: Prompt care seeking and appropriate use of anti-malarial drugs are critical components of malaria prevention and control. This study assessed malaria related perceptions, care seeking behavior and anti-malarial drug use in malaria endemic settings of Ethiopia............
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Insecticide resistance in East Africa—history, distribution and drawbacks on malaria vectors and disease control
Background: Malaria is a major contributor to the global disease burden and a significant impediment to socio-economic development in resource-poor countries. In contrast to improved trends of malaria morbidity and mortality in some parts of the world, malaria has remained a life threatening ..........
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Community perception on beekeeping practices, management, and constraints in Termaber and Basona Werena districts, central Ethiopia
Background: Adequate forage availability coupled with favorable and diversified agroclimatic conditions of Ethiopia creates environmental conditions conducive to the growth of over 7000 species of flowering plants which have supported the existence of large number of bee colonies in the country. ........
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Analysis of asymptomatic and clinical malaria in urban and suburban settings of southwestern Ethiopia in the context of sustaining malaria control and approaching elimination
Background: Malaria intervention in Ethiopia has been strengthened significantly in the past decade. The Ethiopian government recently........
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Similar trends of susceptibility in Anopheles arabiensis and Anopheles pharoensis to Plasmodium vivax infection in Ethiopia
Background: Around half of the global population is living in areas at risk of malaria infection. Plasmodium vivax malaria has become increasingly prevalent and responsible for a high health and socio-economic burden in Ethiopia. The availability of gametocyte carriers and mosquito species susceptible to P. vivax infection ..........
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Identification of different malaria patterns due to Plasmodium falciparum and Plasmodium vivax in Ethiopian children: a prospective cohort study
Background: The identification of epidemiological pattern of infection with Plasmodium falciparum and Plasmodium vivax in malaria-endemic area, where multiple episodes are common, is important for intervention programmes. Methods A longitudinal cohort study based on weekly house-to-house visits was conducted between ........
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High prevalence of gametocyte carriage among individuals with asymptomatic malaria: implications for sustaining malaria control and elimination efforts in Ethiopia
Background: Asymptomatic malaria often contributes to the reservoir of infection in disease transmission. This study reports the prevalence of gametocyte carriage among asymptomatic individuals and assesses the risk factors associated with asymptomatic malaria in the suburbs of Jimma town, .........
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Automated innovative diagnostic, data management and communication tool, for improving malaria vector control in endemic settings
Background: Malaria is a life-threatening disease that caused more than 400,000 deaths in sub-Saharan Africa in 2015. Mass prevention of the disease is best achieved by vector control which heavily relies on the use of insecticides. Monitoring mosquito vector populations ...........
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Evaluation of the efficacy and residual activity of three candidate insecticide formulations for Anopheles gambiae sl in Jimma Zone, Southwestern Ethiopia
Background: One way of evaluating insecticide formulations against malaria vector is to undertake insecticide decay rate study for insecticide deposits on different Wall Surfaces using WHO cone assay. To assess the decay rate of an insecticide .........
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Molecular epidemiology of Plasmodium vivax and Plasmodium falciparum malaria among Duffy-positive and Duffy-negative populations in Ethiopia
Background: Malaria is the most prevalent communicable disease in Ethiopia, with 75% of the country’s landmass classified as endemic for malaria. Accurate information on the distribution and clinical prevalence of Plasmodium vivax and Plasmodium falciparum malaria in endemic areas,.........
Read More2015
Access to and use gaps of insecticide-treated nets among communities in Jimma Zone, southwestern Ethiopia: baseline results from malaria education interventions
Background: Malaria remains one of the major public health concerns in Ethiopia. Use of long- lasting insecticidal nets (LLINs) is the country’s key malaria prevention and control strategy. This study intended to.........
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Malaria incidence and assessment of entomological indices among resettled communities in Ethiopia: a longitudinal study
Background: Population resettlement has been considered among factors that may increase risk of malaria transmission. This study reports, the impact of resettlement on malaria incidence and entomological indices among communities resettled in suburbs of Jimma town, southwestern Ethiopia..........
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Insecticidal decay effects of long-lasting insecticide nets and indoor residual spraying on Anopheles gambiae and Anopheles arabiensis in Western Kenya
Background: Indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs) are the first-line tools for malaria prevention and control in Africa. Vector resistance to insecticides has been extensively studied, however the insecticidal effects.........
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A community-based cross-sectional study of the epidemiology of onchocerciasis in unmapped villages for community directed treatment with ivermectin in Jimma Zone, southwestern …
Background: Human onchocerciasis is a neglected tropical parasitic disease caused by Onchocerca volvulus (O. volvulus) that may result in devastating skin and eye morbidity. Even though the disease is targeted for elimination, there was little or no information on the level of onchocerciasis .........
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PROFILING INSECTICIDE RESISTANCE AND OUTDOOR MALARIA TRANSMISSION IN ETHIOPIA: IMPLICATIONS FOR SUSTAINING CONTROL
Background: This research likely investigates the current status of insecticide resistance in malaria mosquitoes in Ethiopia. By analyzing mosquito populations from different regions, the study may assess the effectiveness of various insecticides and identify areas where resistance is emerging. Additionally, the research may explore the role of outdoor biting..........
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Isolation of Intestinal Parasites of Public Health Importance from Cockroaches (Blattella germanica) in Jimma Town, Southwestern Ethiopia
Background: Cockroaches are claimed to be mechanical transmitters of disease causing microorganisms such as intestinal parasites, bacteria, fungi, and viruses. This study assessed the potential of the German cockroach Blattella germanica in ........
Read More2014
Evaluation of the efficacy of DDT indoor residual spraying and long-lasting insecticidal nets against insecticide resistant populations of Anopheles arabiensis Patton (Diptera …
Background: Indoor Residual Spraying (IRS) and Long-Lasting Insecticidal nets (LLINs) are major malaria vector control tools in Ethiopia. However, recent reports from different parts of the country showed that populations of Anopheles arabiensis, the principal malaria vector,.........
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Water resource developments in Ethiopia: potential benefits and negative impacts on the environment, vector-borne diseases, and food security
Background: To satisfy the growing demand for electricity, Ethiopia plans to increase its electricity production five-fold between 2010 and 2015, mainly through the construction of dams. A literature review shows that while dams can boost power and agricultural..........
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Blood meal sources and sporozoite rates of Anophelines in Gilgel-Gibe dam area, Southwestern Ethiopia
Background: About 520 anopheline mosquitoes were collected from village houses and natural breeding sites in the Gilgele gibe dam area along side with potential hosts in the area to detect blood meal sources and determine sporozoite rates. The specimens were subjected to sporozoite and blood meal ELISA tests. A. arabiensis, A. coustani and A. demeiloni species were identified in which A. arabiensis ........
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Evaluation of the mosquitocidal effect of Birbira (Mellitia ferruginea) seed extract against Anopheles arabiensis (Diptera: Culicidae) from Ethiopia
Background: Mosquito control using insecticides has been the most successful intervention known to reduce malaria prevalence and/or incidence. However, over time success has been hampered due to the development of resistance by mosquitoes,.........
Read More2014